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Kingdom of Saudi Arabia Region
Epidemiology
In KSA, RSV was the most common virus detected with the highest detection rate in children ≤ 2 years 1
RSV was the most commonly detected virus 79% among Saudi children under 5 years of age2
RSV was associated with 97.4% of total viral pathogens1
RSV is the most common pathogen 95.5% causing ALRIs.3
Among 88% of patients, RSV was major causative agent of bronchiolitis2
RSV was the most commonly detected virus 79% among Saudi children under 5 years of age2
RSV was associated with 97.4% of total viral pathogens1
RSV is the most common pathogen 95.5% causing ALRIs.3
Among 88% of patients, RSV was major causative agent of bronchiolitis2
Compliance Study
Increased compliance to Synagis immunoprophylaxis reduced RSV hospitalisation in KSA for six successful RSV seasons5
SYNAGIS was found to be effective and well tolerated in children (<2 years) with CHD for the prevention of severe RSV infection in a study conducted in KSA.5*
Outcomes in patients who recived RSV prophylaxis for six RSV seasons
The average compliance rate was 97%.5†
*Monthly synagis (15 mg/kg IM) was found to be safe, well-tolerated, and effective for the prevention of serious RSV disease in infants and young children with hemodynamically significant CHD. A reduction in the length of hospital stay was observed which was consistent with earlier research.
†The compliance rate was measured by the total number of doses received divided by the total number of doses required.
Gulf Region
Epidemiology
RSV was the most common out of the influenza-like respiratory illness in children ≤ 5 years of age6
Of infants and young children were detected positive with at least one respiratory virus infection of the total samples (N=259) in Oman6
Most prevalent types of viral innfections among infants and children6
Types of Viral Infections
In a study among infants and children admitted to the Sultan Qaboos University Hospital for 1-year period between December 2007 and 2008, a majority of 43% (N=56) were detected with RSV infection out of the total positive samples (N=130).6
Latifa Hospital Study
SYNAGIS IS EFFECTIVE IN REDUCING HOSPITALISATION OF ALL HIGH RISK BABIES <35 wGA7
In one of the biggest NICU units in UAE, hospitalisation due to RSV infection was significantly reduced from 9.23% in the 2012-2013 season to 0.67% in the 2016-2017 season.7
SYNAGIS REDUCES HOSPITALISATION IN ALL HIGH-RISK BABIES <35 wGA7
Adherence Study
INCREASED COMPLIANCE TO SYNAGIS IMMUNOPROPHYLAXIS DECREASES RSV HOSPITALISATIONS DURING RSV SEASONS FOR SUCCESSIVE 3 YEARS FROM 2009-2012 IN QATAR8
RSV hospitalisation and compliance rate of preterm infants treated with at least one dose of palivizumab8
For full safety and prescribing information, please see the SYNAGIS Summary of Product Characteristics (SmPC).
BPD = bronchopulmonary dysplasia; CHD = congenital heart disease; HS-CHD = hemodynamically significant-congenital heart disease; KSA = Kingdom of Saudi Arabia; IM=intra-muscular; MedRA = medical dictionary for regulatory activities RSV = respiratory syncytial virus; wGA = weeks gestational age.
References: 1. Albogami SS, et al. Journal of Infection and Public Health 11 (2018) 183–186 2. Bakir TMF, et al. Journal of Tropical Pediatrics 1998:44:100-103. 3. Bukhari et al. 2013; Vol 34 (11):1151-1155. 4. Al-Shehri MA,et al. West Afr J Med .2005 :24 (4):299-304. 5. Mohammed MHA, et al. Ann Saudi Med. 2021 Jan-Feb;41(1):31-35. 6. Khamis, FA, et al. J Med Virol.2012 :1323-1329. 7. Elhalik M, et al. Can Respir J. 2019;2019:2986286 8. Abushahin A, et al. Int J Gen Med. 2018;11:41-46.