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GLOBAL IMPACT
Epidemiology of RSV: RSV- Related Morbidity and Mortality
MORTALITY
2nd
most common cause of death in children < 1 year old1
~60K
RSV deaths in 2017, and 46% of in-hospital deaths due to RSV occur in infants <6 months old2
MORBIDITY
>3M
of hospital admissions due to RSV occur in infants <6 months old2
>80%
of ALRIs in infants <1 year old are due to RSV3
33M
RSV-associated LRTIs annually in children <5 years old in 20172
90% of children are infected with RSV in the first 2 years of life4
~50% of all cases of pneumonia and up to 90% of the reported cases of bronchiolitis in infacy are due to RSV5
Certain children are at higher risk of presenting with severe RSV3
For full safety and prescribing information, please see the SYNAGIS Summary of Product Characteristics (SmPC).
ALRIs = acute lower respiratory tract infections; LRTIs = lower respiratory tract infections; KSA=Kingdom of Saudi Arabia; PIV=parainfluenza virus ;
RSV = respiratory syncytial virus.
References: 1. Oxford Vaccine Group. Respiratory syncytial virus (RSV). Vaccine Knowledge Project. Updated November 22, 2019. 2. WHO strategy to pilot global respiratory syncytial virus surveillance based on the Global Influenza Surveillance and Response System (GISRS). World Health Organization. 2017. Accessed February 2022. Available from: https://apps.who.int/iris/handle/10665/259853. Accessed on February 2022 3. Piedimonte G, et al. Pediatr Rev. 2014;35:519-530 4. Simoes EA. Lancet. 1999; 354:847-852. 5. Domachowske JB, et al. Clin Microbiol Rev. 1999;12:298-309.