UNDERLYING MECHANISM OF CKD
When CKD is left unchecked, kidney function continues to decline.2,16 Here’s why.
Inside the kidneys,
pressure is building
While patients may experience no early symptoms of CKD, inside their kidneys, intraglomerular pressure is building.2,16
As intraglomerular pressure builds, it slowly destroys nephrons, leading to progressive damage and reduced kidney function.2,3,16
INSIDE THE KIDNEYS,
PRESSURE IS BUILDING
Inside the kidneys,
pressure is building
While patients may experience no early symptoms of CKD, inside their kidneys, intraglomerular pressure is building.2,16
As intraglomerular pressure builds, it slowly destroys nephrons, leading to progressive damage and reduced kidney function.2,3,16
LEARN THE IMPORTANCE OF DIAGNOSING CKD EARLY FROM LEADING EXPERTS
WATCH THE PRESSURE IS ON WEBCAST VIDEO
The Pressure Is On – LIVE WEBCAST
Diagnosing and Improving Outcomes in CKD
CKD can be life-threatening condition that is vastly underdiagnosed. This webcast will provide medical education on disease state awareness to support the diagnosis of CKD and improve patient outcomes. Join leading experts to learn about the importance of diagnosing CKD early.
CKD, chronic kidney disease; CV, cardiovascular; eGFR, estimated glomerular filtration rate; GFR, glomerular filtration rate.
References
- Ryan TP et al. Am J Med. 2007;120(11):981–986.
- Ravera M et al. Am J Kidney Dis. 2011;57(1):71–77.
- GBD Chronic Kidney Disease Collaboration, Lancet. 2020;395(10225):709–733.
- Alabama Department of Public Health. Special Task Force on Chronic Kidney Disease report. April 2007. Accessed 20 November 2020.
https://kipdf.com/special-task-force-on-chronic-kidney-disease-report-april-2007_5ad9b5767f8b9a9b248b45be.html - Kidney Disease: The Basics. National Kidney Foundation. Published 5 April 2021. Accessed 4 February 2022.
https://www.kidney.org/sites/default/files/web_kidneybasics_v4.pdf - Brenner BM et al. N Engl J Med. 2001;345(12):861–869.
- Go AS et al. N Engl J Med. 2004;351(13):1296–1305.
- Levin A et al. Kidney Int. 2014;85(1):49–61.
- Estimated glomerular filtration rate (eGFR). National Kidney Foundation. Reviewed 14 September 2020. Accessed 25 November 2020.
https://www.kidney.org/atoz/content/gfr - Ghaderian SB et al. J Renal Inj Prev. 2014;3(4):109–110.
- Couser WG et al. Kidney Int. 2011;80(12):1258–1270.
- Measurement and estimation of kidney function. Abdominal Key. Accessed 2 November 2021.
https://abdominalkey.com/measurement-and-estimation-of-kidney-function/ - Alyshah AS et al. REVEAL-CKD: Prevalence of and Patient Characteristics Associated With Undiagnosed Stage 3 Chronic Kidney Disease. Poster number: PO2337. Presented at: the American Diabetes Association 81st Scientific Sessions, 25–29 June 2021 (virtual).
- Kidney Disease Stats. National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases. December 2016. Accessed 25 November 2020.
https://www.niddk.nih.gov/health-information/health-statistics/kidney-disease - Yacoub R, Habib H, Lahdo A, et al. Association between smoking and chronic kidney disease: A case control study. BMC Public Health. 2010;10:731.
- Schnaper HW. Pediatr Nephrol. 2014;29(2):193–202.