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Target identification
Discover advanced screening technologies to accelerate novel target identification
Programme details
Submission status: Active
No submission deadline, please apply any time.
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Configure Accordion Item: - What are we looking for?
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Configure Accordion Item: - What are we looking for?
We are looking to collaborate with academic researchers and institutional research centres working on novel, innovative targets aligned to our R&D focus areas as well as those exploring cutting-edge biology.
Configure Accordion Item: - Benefits
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By collaborating with us, you will gain access to high-quality diversity screening sets for use in hit identification. You can opt to screen an entire set or select a subset, depending on the throughput of your assay technology. Currently, we are providing access to the screening collections listed below. We do not provide funding to support this work, but we will provide a letter of support for you to include in your grant funding application.
Configure Accordion Item: - Who is this for?
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Configure Accordion Item: - Who is this for?
This programme is open to basic and applied researchers working in academic settings across all geographies.
Configure Accordion Item: - How to apply
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Find the right screening set for you
Comprising 250,000 compounds that represent the diversity of the entire AstraZeneca screening library, this set has been effectively used for high throughput screening of disease targets to identify novel chemical interactions. We will provide the compounds in assay-ready plates of your preference, and will be on hand to provide follow-up compounds for hit validation, as well as data handling support.
Consisting of 14,000 compounds annotated against 1,600 human targets, this set of compounds is ideal for supporting phenotypic screening and target identification. The library has also been annotated against the secondary effects of compounds which are not commercially available. We provide the compounds in assay-ready plates, and offer “target enhancement” bioinformatic support upon requests.
Consisting of 17,000 fragments with an average of 15 heavy atoms and an average cLogP of 1.3, the fragment library is useful for identifying small molecule, fragment binders that can be starting points for further medchem development.
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