4 October 2023

Results from the largest proteogenomics study to date could transform how we, and others, approach drug discovery. After analysing over 50,000 human exomes from the UK Biobank, we uncovered the links between rare protein-coding genetic variants and nearly 3,000 plasma proteins. The findings, which we are making available to the global scientific community at AZPheWAS.com, are uncovering previously unknown insights into disease biology that can help accelerate the identification of new therapeutic targets and biomarkers.

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