2 November 2023

Endothelin-1 (ET-1) has been shown to be one of the most potent vasoconstrictors. But there are multiple biological effects of endothelin-1 (ET-1) that are recognised including immune regulation, vascular remodelling and fibrosis, while dysregulation of ET-1 and its related pathways have been causally identified as an important mediator in many diseases. By understanding the science behind these mechanisms, we’re exploring new ways to slow or stop disease progression.

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